Bacillus clausii has 3 Resistance Modes

When it comes to gut health, there are few greater allies you can have than that of Bacillus clausii. Once these abundant bacteria colonise the intestine, an existing imbalance is far less likely to affect your daily life by means of symptoms such as abdominal pain, diarrhoea, constipation, and more.

Antibiotic Resistance

Antibiotics are designed to either kill or inhibit the growth of most forms of bacteria. Bacillus clausii bacteria is resistant to this process, and can be used together with most commonly used antibiotics, as it is less likely to be reduced in number. 2

Gastro-Bile Resistance

Many forms of bacteria die when they encounter the acidic contents of the stomach. Bacillus clausii is resistant to this environment, passing through alive in order to colonise the intestine. 1, 3

Thermo Resistance

When exposed to high and low temperatures, Bacillus clausii spores survive and retain their potency. Products containing Bacillus clausii are convenient to carry and travel with, as they do not require refrigeration, and can be added to hot/cold foods and beverages. 1, 3

Frequently Asked Questions

Enterogermina works with the body to restore natural balance in the gut. You probably have got a few questions for us. Check out our FAQ.

  • Bacillus clausii spores have the ability to survive the naturally acidic environment of the stomach, in order to successfully reach the intestinal tract. 1, 3

  • A Bacillus clausii probiotic is instrumental in maintaining gut health. It works to correct existing gut imbalance, as well as prevent future occurrences, helping you to lead a more balanced life from the inside out. 1

  • The four strains of Bacillus clausii bacteria found in Enterogermina products contain specific genes that make them resistant to certain antibiotics. 2

  • Our gut relies on a delicate balance of intestinal flora, also known as the microbiota, for proper functioning. Lifestyle choices, stress, poor diet and antibiotic treatment are all factors that can lead to a lack of intestinal flora. Bacillus clausii spores are a probiotic, restoring the microbiota so that our gut can heal. 1, 3

Gut Disorders

Digestive disorders stemming from intestinal imbalance tend to manifest differently in adults and children. Do any of these symptoms sound familiar?1,3

Gut Disorders in Adults

Gut Disorders in Children


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Enterogermina’s range of products work with the body in delivering specific solutions for various digestive needs. They offer quality good bacteria that not only prevent imbalance and maintain gut health, help to reduce the incidence of symptoms associated with gut disorders in adults and children.


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Learn how different daily triggers could be contributing to intestinal disorder, and how a good probiotic could be the ally you didn't know you needed.

    1. Vecchione A, et al. Compositional quality and potential gastrointestinal behavior of probiotic products commercialized in Italy. Front Med (Lausanne). 2018;5:59.
    2. Abbrescia A, et al. Antibiotic Sensitivity of Bacillus clausii Strains in Commercial Preparation. Clinical Immunology, Endocrine & Metabolic Drugs 2014; 1:102-110.
    3. Ghelardi E, et al. Survival and persistence of Bacillus clausii in the human gastrointestinal tract following oral administration as spore-based probiotic formulation.J Appl Microbiol. 2015;119(2):552-9.
    4. What to know about leaky gut syndrome; Medical News Today, August 2019 [quoted June 2021]
    5. The influence of non-steroidal anti-inflammatory drugs on the gut microbiome, PMC, October 2015 [quoted June 2021]
    6. Whats Causing Your Abdmominal Pain and How to Treat It; Healthline, December 2020 [quoted June 2021]
    7. Jewel, T. (2019) What causes dysbiosis & how is it treated? Healthline. Available at: Accessed on 25/05/2021.
    8. Gastrointestinal diseases during pregnancy: what does the gastroenterologist need to know? PMC, April 2018 [quoted June 2021]
    9. What to know about leaky gut syndrome. Medical News Today, September 2022 [quaoted November 2022]
    10. Side effects-Antibiotics; NHS, May 2019 [quoted June 2021]